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Plasma immune proteome-based risk score predicts survival in advanced gastric cancer treated with PD-1 inhibitors and chemotherapy

BackgroundBlood-based biomarkers that capture systemic immunity could complement tissue-based assays for prognostication in advanced gastric cancer receiving programmed cell death protein 1 (PD-1)–based chemoimmunotherapy. We evaluated whether baseline plasma immune proteomics can stratify clinical...

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Principais autores: Zhouwei Zhan, Ruyu Lin, Yigui Chen, Sha Huang, Luping Lin, Hanchen Zheng, Xiaojie Wang, Xiaoyan Lin, Zengqing Guo, Qiaoting Hu, Bijuan Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-01-01
coleção:Frontiers in Immunology
Assuntos:
gastric cancer
immunotherapy
plasma proteomics
risk score
nomogram
prognosis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1715993/full
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