Diverse Biological Activity of Benzofuroxan/Sterically Hindered Phenols Hybrids

Combining two pharmacophores in a molecule can lead to useful synergistic effects. Herein, we show hybrid systems that combine sterically hindered phenols with dinitrobenzofuroxan fragments exhibit a broad range of biological activities. The modular assembly of such phenol/benzofuroxan hybrids allow...

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Podrobná bibliografie

Hlavní autoři:	Elena Chugunova, Elmira Gibadullina, Kirill Matylitsky, Baurat Bazarbayev, Margarita Neganova, Konstantin Volcho, Artem Rogachev, Nurgali Akylbekov, Hoang Bao Tran Nguyen, Alexandra Voloshina, Anna Lyubina, Syumbelya Amerhanova, Victor Syakaev, Alexander Burilov, Nurbol Appazov, Mukhtar Zhanakov, Leah Kuhn, Oleg Sinyashin, Igor Alabugin
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2023-03-01
Edice:	Pharmaceuticals
Témata:	benzofuroxan sterically hindered phenol anti-cancer activity cytotoxicity apoptosis ROS production
On-line přístup:	https://www.mdpi.com/1424-8247/16/4/499
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!