Transcriptional and functional profiling reveals unique activation of Adapter CAR T cells in acute myeloid leukemia
Abstract Background Chimeric antigen receptor (CAR) T cell therapy has shown great promise in treating malignant diseases, yet its efficacy is often limited by challenges such as controllability and the lack of tumor-specific antigens. Adapter CAR (AdCAR) T cells address these limitations by redirec...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2026-06-01
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| Col·lecció: | Journal of Translational Medicine |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1186/s12967-026-08461-y |
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