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The activation of the metabolic oxaloacetate-pyruvate axis restores influenza A virus replication during impaired glycolysis

Abstract Viruses strongly depend on the host cell for efficient replication and influenza A virus (IAV) amongst others also lead to remarkable changes of the host cell metabolism. The restriction of virus replication through suppression of glucose metabolism has already been described. In addition t...

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Principais autores: Chiara Robin Bojarzyn, Nadine Bieß, Matthias Behrens, Hans-Ulrich Humpf, Stephan Ludwig, Eike R. Hrincius
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2026-05-01
Series:Virology Journal
Acceso en liña:https://doi.org/10.1186/s12985-026-03201-6
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