Dual genomic localizations and gene regulatory functions of MBD-2 with and without NuRD in Caenorhabditis elegans which lacks DNA methylation
Abstract 5-methylcytosine (5mC) DNA methylation is an ancient epigenetic mechanism. Methyl-CpG-binding domain protein 2 or 3 (MBD2/3) is a component of the Nucleosome Remodeling and Deacetylase (NuRD) complex, essential for gene regulation in mammals. The MBD2/3 ortholog is surprisingly preserved ev...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Portfolio
2026-01-01
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| Colección: | Nature Communications |
| Acceso en línea: | https://doi.org/10.1038/s41467-026-68592-0 |
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