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Case Report: Preemptive Treatment With Low-Dose PD-1 Blockade and Azacitidine for Molecular Relapsed Acute Myeloid Leukemia With RUNX1-RUNX1T1 After Allogeneic Hematopoietic Stem Cell Transplantation

Acute myeloid leukemia (AML) patients who develop hematological relapse (HR) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) generally have dismal clinical outcomes. Measurable residual disease (MRD)-directed preemptive interventions are effective approaches to prevent disease p...

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Gardado en:
Principais autores: Yutong Tang, Zhenyang Zhou, Han Yan, Yong You
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Assuntos:
acute myeloid leukemia
allogeneic hematopoietic stem cell transplantation
immune checkpoint inhibitors
preemptive treatment
RUNX1-RUNX1T1
hypomethylating agents
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fimmu.2022.810284/full
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