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Effects of tolvaptan discontinuation in patients with autosomal dominant polycystic kidney disease: a post hoc pooled analysis

Abstract Background Tolvaptan slows kidney function decline in patients with autosomal dominant polycystic kidney disease (ADPKD) who are at risk of rapid progression. Given that treatment requires commitment to long-term use, we evaluated the effects of tolvaptan discontinuation on the trajectory o...

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Principais autores: Michael Lioudis, Xiaolei Zhou, Eric Davenport, Sasikiran Nunna, Holly B. Krasa, Dorothee Oberdhan, Ancilla W. Fernandes
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-06-01
Serier:BMC Nephrology
Fag:
Autosomal dominant polycystic kidney disease (ADPKD)
Tolvaptan
Glomerular filtration rate
Kidney volume
Clinical trial
Treatment
Online adgang:https://doi.org/10.1186/s12882-023-03247-6
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