An analytical pipeline for dose-response effect: laboratory tests assessment and early pregnancy preeclampsia risk

Abstract Background Few studies have explored the associations between early pregnancy laboratory tests and preeclampsia, leaving rich first-trimester data underutilized. This study introduces a pipeline, integrating Generalized Additive Models with dose-response analysis, to elucidate the complex a...

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Detalhes bibliográficos

Principais autores:	Yinyao Ma, Xiao Wang, Jinjiang Mao, Hanlin Lv, Yanhua Ma, Hua Wu, Chun Zhang, Lei Wang, Xuxia Liang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-09-01
coleção:	BMC Pregnancy and Childbirth
Assuntos:	Dose-response effect Generalized additive models Preeclampsia Risk/protective intervals Turning points
Acesso em linha:	https://doi.org/10.1186/s12884-025-07940-2
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