Checkpoint inhibition in combination with an immunoboost of external beam radiotherapy in solid tumors (CHEERS): study protocol for a phase 2, open-label, randomized controlled trial

Abstract Background While the introduction of checkpoint inhibitors (CPIs) as standard of care treatment for various tumor types has led to considerable improvements in clinical outcome, the majority of patients still fail to respond. Preclinical data suggest that stereotactic body radiotherapy (SBR...

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Detalhes bibliográficos

Principais autores:	Mathieu Spaas, Nora Sundahl, Eva Hulstaert, Vibeke Kruse, Sylvie Rottey, Daan De Maeseneer, Veerle Surmont, Annabel Meireson, Lieve Brochez, Dries Reynders, Els Goetghebeur, Robbe Van den Begin, Dirk Van Gestel, Vincent Renard, Piet Dirix, Pieter Mestdagh, Piet Ost
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2021-05-01
coleção:	BMC Cancer
Assuntos:	Head and neck squamous cell carcinoma Melanoma Non-small-cell lung carcinoma Renal cell carcinoma Transitional cell carcinoma Immunotherapy
Acesso em linha:	https://doi.org/10.1186/s12885-021-08088-w
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