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Drug resistance in multiple myeloma: Soldiers and weapons in the bone marrow niche

Multiple myeloma (MM) is still an incurable disease, despite considerable improvements in treatment strategies, as resistance to most currently available agents is not uncommon. In this study, data on drug resistance in MM were analyzed and led to the following conclusions: resistance occurs via int...

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Principais autores: Antonio Giovanni Solimando, Eleonora Malerba, Patrizia Leone, Marcella Prete, Carolina Terragna, Michele Cavo, Vito Racanelli
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-09-01
coleção:Frontiers in Oncology
Assuntos:
multiple myeloma
drug resistance
bone marrow microenvironment
monoclonal gammopathy of undetermined significance
therapeutic targets
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2022.973836/full
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