Microtubule-Targeting Drugs Induce Bcl-2 Phosphorylation and Association with Pin1
Bcl-2 is a critical suppressor of apoptosis that is overproduced in many types of cancer. Phosphorylation of the Bcl-2 protein is induced on serine residues in tumor cells arrested by microtubule-targeting drugs (paclitaxel, vincristine, nocodazole) and has been associated with inactivation of antia...
I tiakina i:
| Ngā kaituhi matua: | , , , , |
|---|---|
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
Elsevier
2001-01-01
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| Rangatū: | Neoplasia: An International Journal for Oncology Research |
| Urunga tuihono: | http://www.sciencedirect.com/science/article/pii/S147655860180018X |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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