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New Pyrazolyl Thioureas Active against the <i>Staphylococcus</i> Genus

To meet the urgent need for new antibacterial molecules, a small library of pyrazolyl thioureas (PTUs) was designed, synthesized and tested against difficult-to-treat human pathogens. The prepared derivatives are characterized by a carboxyethyl functionality on C4 and different hydroxyalkyl chains o...

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Principais autores: Anna Maria Schito, Debora Caviglia, Susanna Penco, Andrea Spallarossa, Elena Cichero, Bruno Tasso, Chiara Brullo
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-03-01
Serier:Pharmaceuticals
Fag:
pyrazoles
pyrazolyl thiourea
antibacterial activity
Gram-positive species
<i>Staphylococcus</i> genus
cystic fibrosis
Online adgang:https://www.mdpi.com/1424-8247/17/3/376
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