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Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis.

c-Myc (hereafter called Myc) belongs to a family of transcription factors that regulates cell growth, cell proliferation, and differentiation. Myc initiates the transcription of a large cast of genes involved in cell growth by stimulating metabolism and protein synthesis. Some of these, like those i...

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Hlavní autoři: Lisa M Nilsson, Tacha Zi Plym Forshell, Sara Rimpi, Christiane Kreutzer, Walter Pretsch, Georg W Bornkamm, Jonas A Nilsson
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2012-01-01
Edice:PLoS Genetics
On-line přístup:http://europepmc.org/articles/PMC3305401?pdf=render
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