Genome-wide association study of thyroid-stimulating hormone highlights new genes, pathways and associations with thyroid disease

Abstract Thyroid hormones play a critical role in regulation of multiple physiological functions and thyroid dysfunction is associated with substantial morbidity. Here, we use electronic health records to undertake a genome-wide association study of thyroid-stimulating hormone (TSH) levels, with a t...

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Библиографические подробности

Главные авторы:	Alexander T. Williams, Jing Chen, Kayesha Coley, Chiara Batini, Abril Izquierdo, Richard Packer, Erik Abner, Stavroula Kanoni, David J. Shepherd, Robert C. Free, Edward J. Hollox, Nigel J. Brunskill, Ioanna Ntalla, Nicola Reeve, Christopher E. Brightling, Laura Venn, Emma Adams, Catherine Bee, Susan E. Wallace, Manish Pareek, Anna L. Hansell, Tõnu Esko, Estonian Biobank Research Team, Daniel Stow, Benjamin M. Jacobs, David A. van Heel, Genes & Health Research Team, William Hennah, Balasubramanya S. Rao, Frank Dudbridge, Louise V. Wain, Nick Shrine, Martin D. Tobin, Catherine John
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Portfolio 2023-10-01
Серии:	Nature Communications
Online-ссылка:	https://doi.org/10.1038/s41467-023-42284-5
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