Frequency-specific medial septal nucleus deep brain stimulation improves spatial memory in MK-801-treated male rats

Background: Few treatments exist for the cognitive symptoms of schizophrenia. Pharmacological agents resulting in glutamate N-methyl-d-aspartate (NMDA) receptor hypofunction, such as MK-801, mimic many of these symptoms and disrupt neural activity. Recent evidence suggests that deep brain stimulatio...

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Detalhes bibliográficos

Principais autores:	Nancy C. Zepeda, Lindsey M. Crown, Sasha Medvidovic, Wooseong Choi, Megha Sheth, Matthew Bergosh, Raymond Gifford, Caroline Folz, Phillip Lam, Gengxi Lu, Robert Featherstone, Charles Y. Liu, Steven J. Siegel, Darrin J. Lee
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2022-08-01
coleção:	Neurobiology of Disease
Assuntos:	MK-801 Hippocampus Medial septal nucleus theta Gamma Deep brain stimulation
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0969996122001486
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