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Regulation of zygotic genome activation by the nucleocytoplasmic ratio

During early development, embryos undergo the maternal-to-zygotic transition (MZT), when control of development shifts from maternal factors to the newly activated zygotic genome. Decades of studies in various model organisms suggest that the nucleocytoplasmic (N/C) ratio is a key regulator of zygot...

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Bibliografiske detaljer
Principais autores: Lily Acker, Hui Chen
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-04-01
Serier:Frontiers in Cell and Developmental Biology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fcell.2026.1819263/full
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