Quantification of overall tumor burden using longitudinal magnetic resonance imaging improves response assessment in orthotopic murine hepatocellular carcinoma models

Abstract Hepatocellular carcinoma (HCC) is one of the most frequent causes of cancer-related death worldwide. Mirroring the complexity of human HCC with its underlying liver disease requires multilocular orthotopic tumor models in mice, where objective tumor quantification in vivo is challenging, es...

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Autori principali:	Isabella Lurje, Wiebke Werner, Nicole Hilbert, Ajay-Mohan Mohan, Kirsten Reers, Anne Schlutt, Maria Kuzminskaya, Yaroslava Shevchenko, Leke Wiering, Ines Eichhorn, Winfried Brenner, Nicola Beindorff, Frank Tacke, Linda Hammerich
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2026-02-01
Serie:	Scientific Reports
Accesso online:	https://doi.org/10.1038/s41598-026-38125-2
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