Loganin, an Iridoid Glycoside, Alleviates Paclitaxel‐Induced Skeletal Muscle Toxicity by Enhancing Mitochondrial Function, Boosting Antioxidant Defenses, and Reducing Cellular Senescence

ABSTRACT Mitochondrial dysfunction and energy imbalance caused by chemotherapy are key contributors to skeletal muscle atrophy, which severely impacts the quality of life in cancer patients. Paclitaxel, a commonly used chemotherapeutic agent, is known to promote muscle wasting and cellular senescenc...

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Detalhes bibliográficos

Principais autores:	Yu‐Fan Chuang, Cai‐Rong Wu, Wan‐Hsuan Chang, Ying‐Jung Su, Hung‐Te Hsu, Fan‐Li Lin, Yi‐Ching Lo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2026-04-01
coleção:	Kaohsiung Journal of Medical Sciences
Assuntos:	cellular senescence loganin mitochondrial dysfunction paclitaxel‐induced myotoxicity skeletal muscle atrophy
Acesso em linha:	https://doi.org/10.1002/kjm2.70117
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