Promotion of beta cell proliferation through DYRK kinase inhibition using the marine natural product breitfussin C
Abstract Pro-inflammatory cytokines, like interleukin-1 beta and interferon gamma, are known to activate signalling pathways causing pancreatic beta cell death and dysfunction, contributing to the onset of diabetes. Targeting cytokine signalling pathways offers a potential strategy to slow or even h...
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| Principais autores: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Portfolio
2025-01-01
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| 叢編: | Scientific Reports |
| 主題: | |
| 在線閱讀: | https://doi.org/10.1038/s41598-025-85178-w |
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