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CircRNA0052011 modulates DNA damage and repair via FEN1 ubiquitination to mitigate polystyrene nanoplastics-induced genotoxicity in the lung

Polystyrene nanoplastics (PS-NPs) are one type of environmental pollutants that can penetrate biological barriers and accumulate within cells due to their small particle size. This characteristic raises concerns about their potential respiratory toxicity. However, the impact of PS-NPs on genomic sta...

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Principais autores: Meiqi Lan, Chenghui Zhong, Xiaole Xu, Mengnan He, Lieyang Fan, Wenfeng Lu, Liqiu Qiu, Jingwen Fang, Jiajing Wang, Shaojuan Wang, Zhizun Deng, Yingxin Chen, Lan Qiu, Xinyu Chen, Yiguo Jiang, Yun Zhou
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2026-04-01
coleção:Environment International
Assuntos:
Nanoplastics
CircRNA
DNA damage
Genotoxicity
Respiratory toxicity
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0160412026001698
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