A mechanistic model of pure and lipidic α-synuclein aggregation for advancing Parkinson’s therapies
Abstract Alpha-synuclein (aSyn) plays a crucial role in Parkinson’s disease, with various aggregates proposed as pathogenic triggers and therapeutic targets. However, anti-aSyn aggregation compounds often fail due to limited knowledge of the underlying molecular basis. In particular, interactions wi...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Portfolio
2025-06-01
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| Col·lecció: | Communications Chemistry |
| Accés en línia: | https://doi.org/10.1038/s42004-025-01558-3 |
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