Rapid monocyte infiltration following retinal detachment is dependent on non-canonical IL6 signaling through gp130

Abstract Background Retinal detachment (RD) can lead to proliferative vitreoretinopathy (PVR), a leading cause of intractable vision loss. PVR is associated with a cytokine storm involving common proinflammatory molecules like IL6, but little is known about the source and downstream signaling of IL6...

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Principais autores:	Xinlei Wang, Eric B. Miller, Mayank Goswami, Pengfei Zhang, Kaitryn E. Ronning, Sarah J. Karlen, Robert J. Zawadzki, Edward N. Pugh, Marie E. Burns
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2017-06-01
Serija:	Journal of Neuroinflammation
Teme:	Retinal detachment Monocyte Interleukin 6 IL6 Rα gp130 CCL2
Online dostop:	http://link.springer.com/article/10.1186/s12974-017-0886-6
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