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Regulation of human neurotropic JC virus replication by alternative splicing factor SF2/ASF in glial cells.

The human neurotropic virus, JC virus (JCV), is the etiologic agent of the fatal demyelinating disease of the central nervous system, Progressive Multifocal Leukoencephalopathy (PML) that is seen primarily in immunodeficient individuals. Productive infection of JCV occurs only in glial cells, and th...

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Autori principali: Ilker Kudret Sariyer, Kamel Khalili
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2011-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3031499?pdf=render
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