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Genomic Insertion of a Heterologous Acetyltransferase Generates a New Lipopolysaccharide Antigenic Structure in Brucella abortus and Brucella melitensis

Brucellosis is a bacterial zoonosis of worldwide distribution caused by bacteria of the genus Brucella. In Brucella abortus and Brucella melitensis, the major species infecting domestic ruminants, the smooth lipopolysaccharide (S-LPS) is a virulence factor. This S-LPS carries a N-formyl-perosamine h...

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Principais autores: Estrella Martínez-Gómez, Jonas Ståhle, Yolanda Gil-Ramírez, Amaia Zúñiga-Ripa, Mona Zaccheus, Ignacio Moriyón, Maite Iriarte, Göran Widmalm, Raquel Conde-Álvarez
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-05-01
coleção:Frontiers in Microbiology
Assuntos:
lipopolysaccharide (LPS)
bacterial pathogenesis
bacteria
vaccine development
virulence factor
antigen
Acesso em linha:https://www.frontiersin.org/article/10.3389/fmicb.2018.01092/full
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