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CT-guided intratumoral immunotherapy for advanced solid tumors: a prospective clinical study of safety and systemic antitumor effects

BackgroundSystemic administration of immunotherapy via intravenous injection is frequently associated with off-target toxicity throughout the body. In contrast, intratumoral injection has emerged as a promising strategy to mitigate systemic adverse effects. However, data regarding the safety of CT-g...

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Principais autores: Yongqiong Ou, Jian Zhang, Hongye Tan, Binjia He, Tianheng Li, Manting Liu, Cheng Zhi, Junhao Huang, Ming Li, Shenghua Zuo, Noor Ul Huda Shah, Yuning Chen, Junjian Huang, Dongni Chen, Ruzhai Qin, Xufeng Li, Hui Lian, Qingde Wu, Hainan Yang, Zhenfeng Zhang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-07-01
Serier:Frontiers in Immunology
Fag:
advanced solid tumors
CT guidance
immunotherapy
intratumoral injection
safety
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1869154/full
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