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Upregulation of Peroxiredoxin-2 in Well-Differentiated Pancreatic Neuroendocrine Tumors and Its Utility as a Biomarker for Predicting the Response to Everolimus

Pancreatic neuroendocrine neoplasms (pNENs) account for 2–3% of pancreatic malignancies. Peroxiredoxins (Prdxs), which are major cellular antioxidants, are involved in multiple oncogenic signaling pathways. We investigated the role of peroxiredoxin-2 in QGP-1 human pNEN cell line and patient-derived...

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Principais autores: Eui Joo Kim, Yoon Jae Kim, Hye In Lee, Seok-Hoo Jeong, Hyo Jung Nam, Jae Hee Cho
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-11-01
coleção:Antioxidants
Assuntos:
pancreatic neuroendocrine neoplasm
peroxiredoxin
mTOR inhibitor
everolimus
Acesso em linha:https://www.mdpi.com/2076-3921/9/11/1104
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