Cbl ubiquitin ligases mediate the inhibition of natural killer cell activity
Natural killer (NK) cells are essential for killing transformed and virally infected cells. To prevent auto-reactivity, NK cell activation is inhibited by inhibitory receptors that activate the tyrosine phosphatase SHP-1, which dephosphorylates signaling molecules crucial for NK cell activation. Ini...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis Group
2016-11-01
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| Series: | Communicative & Integrative Biology |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/19420889.2016.1216739 |
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