Gut microbiota-derived glutathione from metformin treatment alleviates intestinal ferroptosis induced by ischemia/reperfusion

Abstract Background Intestinal ischemia/reperfusion injury (IIRI) is a life-threatening condition caused by multiple organ and system failures induced by dysbiosis and gut leakage. Metformin has demonstrated efficacy in protecting against IIRI, although the precise role of the gut microbiota in the...

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主要な著者:	Fangyan Wang, Xinyu Wang, Chaoyi Wang, Wangxin Yan, Junpeng Xu, Zhengyang Song, Mingli Su, Jingjing Zeng, Qiannian Han, Gaoyi Ruan, Eryao Zhang, Wantie Wang
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2025-05-01
シリーズ:	BMC Medicine
主題:	Metformin Intestinal ischemia/reperfusion injury Ferroptosis Gut microbiota Glutathione
オンライン･アクセス:	https://doi.org/10.1186/s12916-025-04119-6
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