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Image-based high-throughput mapping of TGF-β-induced phosphocomplexes at a single-cell level

To improve our ability to monitor cellular responses to e.g. cytokines or drugs, Lönn et al have developed a semi-automated system for large-scale in situ proximity ligation assays (isPLA) in HaCAT keratinocyte cells. Their approach expands the scope for image-based single cell analyses by combining...

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Principais autores: Peter Lönn, Rasel A. Al-Amin, Ehsan Manouchehri Doulabi, Johan Heldin, Radiosa Gallini, Johan Björkesten, Johan Oelrich, Masood Kamali-Moghaddam, Ulf Landegren
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2021-11-01
coleção:Communications Biology
Acesso em linha:https://doi.org/10.1038/s42003-021-02798-4
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