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Elevated microsatellite instability at selected tetranucleotide (EMAST) repeats in gastric cancer: a distinct microsatellite instability type with potential clinical impact?

Abstract We investigated the clinical impact of elevated microsatellite instability at selected tetranucleotide (EMAST) repeats in the context of neoadjuvant chemotherapy (CTx) in gastric/gastro‐oesophageal adenocarcinomas. We analysed 583 resected tumours (272 without and 311 after CTx) and 142 tum...

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Principais autores: Anna‐Lina Herz, Sarah Wisser, Meike Kohlruss, Julia Slotta‐Huspenina, Moritz Jesinghaus, Bianca Grosser, Katja Steiger, Alexander Novotny, Alexander Hapfelmeier, Thomas Schmidt, Matthias M Gaida, Wilko Weichert, Gisela Keller
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2022-05-01
Serier:The Journal of Pathology: Clinical Research
Fag:
EMAST
microsatellite instability
gastric adenocarcinoma
neoadjuvant chemotherapy
prognosis
Online adgang:https://doi.org/10.1002/cjp2.257
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