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OX40 facilitates control of a persistent virus infection.

During acute viral infections, clearance of the pathogen is followed by the contraction of the anti-viral T cell compartment. In contrast, T cell responses need to be maintained over a longer period of time during chronic viral infections in order to control viral replication and to avoid viral spre...

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Bibliografiske detaljer
Principais autores: Tobias Boettler, Friedrich Moeckel, Yang Cheng, Maximilian Heeg, Shahram Salek-Ardakani, Shane Crotty, Michael Croft, Matthias G von Herrath
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2012-09-01
Serier:PLoS Pathogens
Online adgang:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002913&type=printable
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