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Impact of Novel Resistance Profiles in HIV-1 Reverse Transcriptase on Phenotypic Resistance to NVP

Objective. To clarify the impact of H221Y mutation on drug resistance to NVP. Methods. 646 bp HIV-1 pol gene fragments (from 592 to 1237 nucleotide) with different NNRTIs mutation profiles from AIDS patients receiving antiretroviral therapy containing NVP regimens were introduced into pNL4-3 backbon...

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Bibliografske podrobnosti
Principais autores: Liyan Jiao, Hanping Li, Lin Li, Daomin Zhuang, Yongjian Liu, Zuoyi Bao, Siyang Liu, Jingyun Li
Format: Artigo
Jezik:Inglês
Izdano: Wiley 2012-01-01
Serija:AIDS Research and Treatment
Online dostop:http://dx.doi.org/10.1155/2012/637263
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