TGR5 dysfunction underlies chronic social defeat stress via cAMP/PKA signaling pathway in the hippocampus

Abstract Major depressive disorder (MDD) is a debilitating mental health disorder that has a wide impact on many patients and has imposed a heavy burden on society in recent years. However, the specific pathogenesis of depression remains to be elucidated. Numerous studies have shown that metabolic d...

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Bibliografische gegevens

Hoofdauteurs:	Xiangyu Chen, Qinji Zhou, Yong He, Yue Wang, Yanyi Jiang, Yi Ren, Yikun Ren, Junchao Cai, Heming Yu, Chong Chen, Ke Cheng, Peng Xie
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Nature Publishing Group 2025-10-01
Reeks:	Translational Psychiatry
Online toegang:	https://doi.org/10.1038/s41398-025-03599-7
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