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Molecular subtypes of ALS are associated with differences in patient prognosis

Variability in ALS disease onset and progression are poorly understood. Our work identifies three distinct molecular states in post-mortem tissue that capture some of the observed differences in patient age of onset and survival.

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Detalhes bibliográficos
Principais autores: Jarrett Eshima, Samantha A. O’Connor, Ethan Marschall, NYGC ALS Consortium, Robert Bowser, Christopher L. Plaisier, Barbara S. Smith
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2023-01-01
coleção:Nature Communications
Acesso em linha:https://doi.org/10.1038/s41467-022-35494-w
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