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Reductive amination of ω-conotoxin MVIIA: synthesis, determination of modification sites, and self-assembly

Abstract Peptide drugs have disadvantages such as low stability, short half-life and side effects, which limit their widespread use in clinical practice. Therefore, peptide drugs can be modified to improve these disadvantages. Numerous studies have shown that alkyl-modified peptide drugs can self-as...

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Principais autores: Xiufang Ding, Yue Wang, Sida Zhang, Ruihua Zhang, Dong Chen, Changcai Liu, Jianfu Xu, Long Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Springer 2024-03-01
coleção:Amino Acids
Assuntos:
Reductive amination
MVIIA
Conotoxin
Modification
Self-assembly
Acesso em linha:https://doi.org/10.1007/s00726-023-03366-2
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