Nrf2/Keap1/ARE regulation by plant secondary metabolites: a new horizon in brain tumor management

Abstract Brain cancer is regarded as one of the most life-threatening forms of cancer worldwide. Oxidative stress acts to derange normal brain homeostasis, thus is involved in carcinogenesis in brain. The Nrf2/Keap1/ARE pathway is an important signaling cascade responsible for the maintenance of red...

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Hlavní autoři:	Saikat Dewanjee, Hiranmoy Bhattacharya, Chiranjib Bhattacharyya, Pratik Chakraborty, Joshua Fleishman, Athanasios Alexiou, Marios Papadakis, Saurabh Kumar Jha
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-10-01
Edice:	Cell Communication and Signaling
Témata:	Antioxidants ARE Brain cancer Keap1 Nrf2 Oxidative stress
On-line přístup:	https://doi.org/10.1186/s12964-024-01878-2
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