Effects of Tumor-Derived Exosome Programmed Death Ligand 1 on Tumor Immunity and Clinical Applications

Programmed death ligand 1 (PD-L1) is a typical immune surface protein that binds to programmed cell death 1 (PD-1) on T cells through its extracellular domain. Subsequently, T cell activity is inhibited, and tumor immune tolerance is enhanced. Anti-PD-1/PD-L1 immune checkpoint therapy blocks the com...

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Hauptverfasser:	Bo Shao, Qin Dang, Zhuang Chen, Chen Chen, Quanbo Zhou, Bingbing Qiao, Jinbo Liu, Shengyun Hu, Guixian Wang, Weitang Yuan, Zhenqiang Sun
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2021-10-01
Schriftenreihe:	Frontiers in Cell and Developmental Biology
Schlagworte:	exosome PD-L1 PD-1 tumor immunity biomarker
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fcell.2021.760211/full
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