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Mechanism of Qingjie Fuzheng Granules on alleviating 5-FU chemotherapy-induced intestinal mucositis in a mouse model of Colorectal Cancer by regulating Cathepsin B/NLRP3 pathway

ObjectiveBased on the Cathepsin B/NLRP3 pathway to explore the therapeutic effect and action mechanism of intestinal mucositis after 5-fluorouracil （5-FU） chemotherapy in colorectal carcinoma mice.MethodsTwenty-four male BALB/c mice were selected for subcutaneous inoculation of CT26 cells in the axi...

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Principais autores: Yuan Yingfei, Lin Jiumao, Lin Minghe, Zhao Jinyan, Chen Xuzheng, Liu Jinhong, Zhu Xiaoqin
Format: Artigo
Sprog:Inglês
Udgivet: Editorial Office of Rehabilitation Medicine 2024-10-01
Serier:康复学报
Fag:
colorectal cancer
Cathepsin B/NLRP3
intestinal mucositis
5-Fluorouracil
Qingjie Fuzheng Granules
Online adgang:http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2025.01015
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