Pancreatic stem cells originate during the pancreatic progenitor developmental stage

Previously isolated adult pancreatic precursors called pancreatic multipotent progenitors (which make both pancreatic endocrine and exocrine cell types) originate from the Pancreatic Duodenal Homeobox 1 (PDX1) pancreatic developmental lineage. The embryonic time point at which adult pancreatic multi...

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Autori principali: Krystal Jacques, Brenda L. K. Coles, Derek van der Kooy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2025-02-01
Serie:Frontiers in Cell and Developmental Biology
Soggetti:
pancreatic progenitor
pancreatic development
clonal assays
human ES cell differentiation
mouse primary cell culture
beta cell (β cell)
Accesso online:https://www.frontiersin.org/articles/10.3389/fcell.2025.1521411/full
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