Neuronal death in pneumococcal meningitis is triggered by pneumolysin and RrgA interactions with β-actin.

Neuronal damage is a major consequence of bacterial meningitis, but little is known about mechanisms of bacterial interaction with neurons leading to neuronal cell death. Streptococcus pneumoniae (pneumococcus) is a leading cause of bacterial meningitis and many survivors develop neurological sequel...

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Detalhes bibliográficos

Principais autores:	Mahebali Tabusi, Sigrun Thorsdottir, Maria Lysandrou, Ana Rita Narciso, Melania Minoia, Chinmaya Venugopal Srambickal, Jerker Widengren, Birgitta Henriques-Normark, Federico Iovino
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2021-03-01
coleção:	PLoS Pathogens
Acesso em linha:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009432&type=printable
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