Characterization and clinical evaluation of microsatellite instability and loss of heterozygosity within tumor-related genes in colorectal cancer

Abstract Background Microsatellite instability (MSI) is a biomarker for better outcomes in colorectal cancer (CRC). However, this conclusion is controversial. In addition, MSs can be a useful marker for loss of heterozygosity (LOH) of genes, but this finding has not been well studied. Here, we aimed...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Xueyun Huo, Dandan Feng, Shuangyue Zhang, Zhenkun Li, Xiaohong Li, Changlong Li, Meng Guo, Jin Wang, Zhongtao Zhang, Qingxian Lu, Xiaoyan Du, Zhigang Bai, Zhenwen Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2021-09-01
coleção:	BMC Medical Genomics
Assuntos:	Microsatellite instability Loss of heterozygosity Colorectal cancer Prognosis Tumor-related genes
Acesso em linha:	https://doi.org/10.1186/s12920-021-01051-5
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!