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Inhibiting N-acyl-homoserine lactone synthesis and quenching Pseudomonas quinolone quorum sensing to attenuate virulence

Bacteria sense their own population size, tune the expression of responding genes and behave accordingly to environmental stimuli by secreting signalling molecules. This phenomenon is termed as quorum sensing (QS). By exogenously manipulating the signal transduction bacterial population behaviours c...

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Principais autores: Kok Gan eChan, Yi-Chia eLiu, Chien-Yi eChang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015-10-01
Serier:Frontiers in Microbiology
Fag:
Pseudomonas aeruginosa
PQS
quorum sensing (QS)
quorum quenching
N-Acyl-homoserine lactone
alkylquinolone
Online adgang:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01173/full
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