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Discovery of senolytics using machine learning

Abstract Cellular senescence is a stress response involved in ageing and diverse disease processes including cancer, type-2 diabetes, osteoarthritis and viral infection. Despite growing interest in targeted elimination of senescent cells, only few senolytics are known due to the lack of well-charact...

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Bibliografiske detaljer
Principais autores: Vanessa Smer-Barreto, Andrea Quintanilla, Richard J. R. Elliott, John C. Dawson, Jiugeng Sun, Víctor M. Campa, Álvaro Lorente-Macías, Asier Unciti-Broceta, Neil O. Carragher, Juan Carlos Acosta, Diego A. Oyarzún
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2023-06-01
Serier:Nature Communications
Online adgang:https://doi.org/10.1038/s41467-023-39120-1
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