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Ripk2 Dictates Nod2 Mediated Chemotherapy Resistance Through Inhibiting Pyroptosis

Aim or purpose: Cisplatin resistance in HNSCC remains a major therapeutic challenge. Evidence suggests that intratumoral microbiota modulates chemotherapy resistance by reshaping the tumor microenvironment, yet the underlying mechanisms and targeted strategies remain elusive. We found that the NOD2-...

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Hovedforfatter: Xin Guo
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-10-01
Serier:International Dental Journal
Fag:
RIPK2
NOD pathway
pyroptosis
cisplatin resistance
bacterial vesicles
Online adgang:http://www.sciencedirect.com/science/article/pii/S0020653925051366
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