β-catenin inhibition disrupts the homeostasis of osteogenic/adipogenic differentiation leading to the development of glucocorticoid-induced osteonecrosis of the femoral head

Glucocorticoid-induced osteonecrosis of the femoral head (GONFH) is a common refractory joint disease characterized by bone damage and the collapse of femoral head structure. However, the exact pathological mechanisms of GONFH remain unknown. Here, we observed abnormal osteogenesis and adipogenesis...

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Κύριοι συγγραφείς:	Chenjie Xia, Huihui Xu, Liang Fang, Jiali Chen, Wenhua Yuan, Danqing Fu, Xucheng Wang, Bangjian He, Luwei Xiao, Chengliang Wu, Peijian Tong, Di Chen, Pinger Wang, Hongting Jin
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	eLife Sciences Publications Ltd 2024-02-01
Σειρά:	eLife
Θέματα:	osteonecrosis of the femoral head β-catenin Col2+ lineage Glucocorticoid osteogenic/adipogenic differentiation
Διαθέσιμο Online:	https://elifesciences.org/articles/92469
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