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Role of Pyridine Nitrogen in Palladium-Catalyzed Imine Hydrolysis: A Case Study of (E)-1-(3-bromothiophen-2-yl)-N-(4-methylpyridin-2-yl)methanimine

In the present study, 4-methylpyridin-2-amine was reacted with 3-bromothiophene-2-carbaldehyde and the Schiff base (E)-1-(3-bromothiophen-2-yl)-N-(4-methylpyridin-2-yl)methanimine was obtained in a 79% yield. Coupling of the Schiff base with aryl/het-aryl boronic acids under Suzuki coupling reaction...

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Principais autores: Gulraiz Ahmad, Nasir Rasool, Komal Rizwan, Ataf Ali Altaf, Umer Rashid, Mohd Zobir Hussein, Tariq Mahmood, Khurshid Ayub
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-07-01
coleção:Molecules
Assuntos:
Thiophene
carbaldehyde
hydrolysis
cleavage
palladium
imine.
Acesso em linha:https://www.mdpi.com/1420-3049/24/14/2609
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