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Pramipexole restores behavioral inhibition in highly impulsive rats through a paradoxical modulation of frontostriatal networks

Abstract Impulse control disorders (ICDs), a wide spectrum of maladaptive behaviors which includes pathological gambling, hypersexuality and compulsive buying, have been recently suggested to be triggered or aggravated by treatments with dopamine D2/3 receptor agonists, such as pramipexole (PPX). De...

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Detalhes bibliográficos
Principais autores: Robin Magnard, Maxime Fouyssac, Yvan M. Vachez, Yifeng Cheng, Thibault Dufourd, Carole Carcenac, Sabrina Boulet, Patricia H. Janak, Marc Savasta, David Belin, Sebastien Carnicella
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2024-02-01
coleção:Translational Psychiatry
Acesso em linha:https://doi.org/10.1038/s41398-024-02804-3
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