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Targeting mTOR signaling pathways in multiple myeloma: biology and implication for therapy

Abstract Multiple Myeloma (MM), a cancer of terminally differentiated plasma cells, is the second most prevalent hematological malignancy and is incurable due to the inevitable development of drug resistance. Intense protein synthesis is a distinctive trait of MM cells, supporting the massive produc...

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Hlavní autoři: Yanmeng Wang, Niels Vandewalle, Kim De Veirman, Karin Vanderkerken, Eline Menu, Elke De Bruyne
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2024-06-01
Edice:Cell Communication and Signaling
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On-line přístup:https://doi.org/10.1186/s12964-024-01699-3
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