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Olfactory bulb anomalies in KBG syndrome mouse model and patients

Abstract ANKRD11 (ankyrin repeat domain 11) is a chromatin regulator and the only gene associated with KBG syndrome, a rare neurodevelopmental disorder. We have previously shown that Ankrd11 regulates murine embryonic cortical neurogenesis. Here, we show a novel olfactory bulb phenotype in a KBG syn...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Kara Goodkey, Anita Wischmeijer, Laurence Perrin, Adrianne E. S. Watson, Leenah Qureshi, Duccio Maria Cordelli, Francesco Toni, Maria Gnazzo, Francesco Benedicenti, Monique Elmaleh-Bergès, Karen J. Low, Anastassia Voronova
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2024-04-01
Schriftenreihe:BMC Medicine
Schlagworte:
Anosmia
Olfactory nerve
Olfactory bulb
Rostral migratory stream
RMS
Neural stem cell
Online-Zugang:https://doi.org/10.1186/s12916-024-03363-6
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