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The effect of the PKR inhibitor, 2-aminopurine, on the replication of influenza A virus, and segment 8 mRNA splicing

Influenza A virus (IAV) is a negative-sense, single-stranded RNA virus, whose genome consists of eight segments encoding multiple structural and non-structural proteins essential for viral replication and host immune evasion. Among these, segment 8 encodes two primary non-structural proteins  NS1, c...

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Principais autores: Lorent Dagny, Nowak Rafal, Gazecka Monika, Zmora Pawel, Onyekaa Elzbieta Lenartowicz
Formato: Artigo
Idioma:Inglês
Publicado em: De Gruyter 2025-04-01
coleção:Open Life Sciences
Assuntos:
influenza a virus
mrna splicing
pseudoknot structure
double-stranded rna-activated protein kinase
non-structural proteins ns1 and ns2
Acesso em linha:https://doi.org/10.1515/biol-2025-1098
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